Author : Matthew Walker
TLDR :
- Sleep enriches our ability to learn and make connections in our brain
- Sleep helps the long term memory
- Sleeps permits to make logical decisions
- Sleep recalibrates our emotions,
- Sleep enhances muscle/motor memory
- Sleep restocks our immune system,
- Sleep fine-tunes our metabolism
- Sleep regulates our appetite (feeling of fullness, hunger)
- Sleep and dreaming creates a virtual reality space in which the brain melds past and present knowledge, including trauma and bad experiences
- Sleep permits to fight off Alzheimer and other deceases
- Sleep promotes creativity
- You need 7-8 hours of sleep, the myth of the successful man that only sleeps <5hours is not good and should not be promoted
- You can’t get back sleep credits
Sleep drivers :
- circadian rhythm : The internal twenty-four-hour clock within your brain communicates its daily circadian rhythm signal to every other region of your brain and every organ in your body. Your twenty-four-hour tempo helps to determine when you want to be awake and when you want to be asleep.
- adenosine : sleep pressure. At this very moment, a chemical called adenosine is building up in your brain. It will continue to increase in concentration with every waking minute that elapses. The longer you are awake, the more adenosine will accumulate. Think of adenosine as a chemical barometer that continuously registers the amount of
elapsed time since you woke up this morning.
Kinds of sleep :
rapid eye movement : (REM) sleep, the stage in which humans principally dream and NREM – non rapid eye movemen ( 4 diffwerent stages)
Interesting elements :
P7 : Within the brain, sleep enriches a diversity of functions, including our ability to learn, memorize, and make logical decisions and choices. Benevolently servicing our psychological health, sleep recalibrates our emotional brain circuits, allowing us to navigate next-day social and psychological challenges with cool-headed composure.
P25 : Other studies of pilots, cabin crew members, and shift workers have reported additionally disquieting consequences, including far higher rates of cancer and type 2 diabetes than the general population—or even carefully controlled match individuals who do not travel as much.
P45 : Similar to an unbalanced diet in which you only eat carbohydrates and are left malnourished by the absence of protein, short-changing the brain of either NREM or REM sleep—both of which serve critical, though different, brain and body functions—results in a myriad of physical and mental ill health
P52 : Each and every night, REM sleep ushers you into a preposterous theater wherein you are treated to a bizarre, highly associative carnival of autobiographical themes. When it comes to information processing, think of the wake state principally as reception (experiencing and constantly learning the world around you), NREM sleep as reflection (storing and strengthening those raw ingredients of new facts and skills), and REM sleep as integration (interconnecting these raw ingredients with each other, with all past experiences, and, in doing so, building an ever
more accurate model of how the world works, including innovative insights and problem-solving abilities).
P61 : More intriguing than the poverty of REM sleep in this aquatic corner of the mammalian kingdom is the fact that birds and mammals evolved separately. REM sleep may therefore have been birthed twice in the course of evolution:
once for birds and once for mammals. A common evolutionary pressure may still have created REM sleep in both, in the same way that eyes have evolved separately and independently numerous times across different phyla
throughout evolution for the common purpose of visual perception. When a theme repeats in evolution, and independently across unrelated lineages, it often signals a fundamental need.
P65 : But if you bring that person into a sleep laboratory, or take them to a hotel—both of which are unfamiliar sleep environments—one half of the brain sleeps a little lighter than the other, as if it’s standing guard with just a tad more vigilance due to the potentially less safe context that the conscious brain has registered while awake. The more nights an individual sleeps in the new location, the more similar the sleep is in each half of the brain. It is perhaps the reason why so many of us sleep so poorly the first night in a hotel room
P68 : Should you ever have to give a presentation at work, for your own sake—and that of the conscious state of your listeners—if you can, avoid the midafternoon slot.
P73 : Related, the REM-sleep gift of facilitating accurate recognition and comprehension allows us to make more intelligent decisions and actions as a consequence. More specifically, the coolheaded ability to regulate our emotions each day—a key to what we call emotional IQ—depends on getting sufficient REM sleep night after night. (If your mind immediately jumped to particular colleagues, friends, and public figures who lack these traits, you may well wonder about how much sleep, especially late-morning REM-rich sleep, they are getting.)
P75 : Now we can appreciate what I believe to be a classic, self-fulfilling positive cycle of evolution. Our shift from tree to ground sleeping instigated an ever more bountiful amount of relative REM sleep compared with other primates, and from this bounty emerged a steep increase in cognitive creativity, emotional intelligence, and thus social complexity. This, alongside our increasingly dense, interconnected brains, led to improved daily (and nightly) survival strategies. In turn, the harder we worked those increasingly developed emotional and creative circuits of the brain during the day, the greater was our need to service and recalibrate these ever-demanding neural systems at night with more REM sleep. As this positive feedback loop took hold in exponential fashion, we formed, organized, maintained, and deliberatively shaped ever larger social groups.
P86: Prior to birth, and soon after, the challenge for development was to build and add vast numbers of neural highways and interconnections that become a fledgling brain. As we have discussed, REM sleep plays an essential role in this proliferation process, helping to populate brain neighborhoods with neural connectivity, and then activate those pathways with a healthy dose of informational bandwidth. But since this first round of brain wiring is purposefully overzealous, a second round of remodeling must take place. It does so during late childhood and adolescence. Here, the architectural goal is not to scale up, but to scale back for the goal of efficiency and effectiveness. The time of adding brain connections with the help of REM sleep is over. Instead, pruning of connections becomes the order of the day or, should I say, night. Enter the sculpting hand of deep NREM sleep.
P88 : Feinberg proposed that the rise and fall of deep-sleep intensity were helping lead the maturational journey through the precarious heights of adolescence, followed by safe onward passage into adulthood. Recent findings have
supported his theory. As deep NREM sleep performs its final overhaul and refinement of the brain during adolescence, cognitive skills, reasoning, and critical thinking start to improve, and do so in a proportional manner with that NREM sleep change.
P 127 : My final discovery, in what spanned almost a decade of research, identified the type of sleep responsible for the overnight motor-skill enhancement, carrying with it societal and medical lessons. The increases in speed and accuracy, underpinned by efficient automaticity, were directly related to the amount of stage 2 NREM, especially in the last two hours of an eight-hour night of sleep (e.g., from five to seven a.m., should you have fallen asleep at eleven p.m.).
P137 : Similarly problematic is baseline resetting. With chronic sleep restriction over months or years, an individual will actually acclimate to their impaired performance, lower alertness, and reduced energy levels. That low-level exhaustion becomes their accepted norm, or baseline. Individuals fail to recognize how their perennial state of sleep deficiency has come to compromise their mental aptitude and physical vitality, including the slow accumulation of ill health. A link between the former and latter is rarely made in their mind.
P140 : After thirty years of intensive research, we can now answer many of the questions posed earlier. The recycle rate of a human being is around sixteen hours. After sixteen hours of being awake, the brain begins to fail. Humans need more than seven hours of sleep each night to maintain cognitive performance. After ten days of just seven hours of sleep, the brain is as dysfunctional as it would be after going without sleep for twenty-four hours. Three full nights of recovery sleep (i.e., more nights than a weekend) are insufficient to restore performance back to normal levels after a week of short sleeping. Finally, the human mind cannot accurately sense how sleep-deprived it is when sleep-deprived.
P156 : In other words, if you don’t sleep the very first night after learning, you lose the chance to consolidate those memories, even if you get lots of “catch-up” sleep thereafter. In terms of memory, then, sleep is not like the bank. You cannot accumulate a debt and hope to pay it off at a later point in time. Sleep for memory consolidation is an all-or-nothing event. It is a concerning result in our 24/7, hurry-up, don’t-wait society.
P160 : One piece of toxic debris evacuated by the glymphatic system during sleep is amyloid protein— the poisonous element associated with Alzheimer’s disease. Other dangerous metabolic waste elements that have links to Alzheimer’s disease are also removed by the cleaning process during sleep, including a protein called tau, as well as stress molecules produced by neurons when they combust energy and oxygen during the day. Should you experimentally prevent a mouse from getting NREM sleep, keeping it awake instead, there is an immediate increase in amyloid deposits within the brain. Without sleep, an escalation of poisonous Alzheimer’s-related protein accumulated in the brains of the mice, together with several other toxic metabolites. Phrased differently, and perhaps more simply, wakefulness is low-level brain damage, while sleep is neurological sanitation.
P164: As we approach midlife, and our body begins to deteriorate and health resilience starts its decline, the impact of insufficient sleep on the cardiovascular system escalates. Adults forty-five years or older who sleep fewer than six hours a night are 200 percent more likely to have a heart attack or stroke during their lifetime, as compared with those sleeping seven to eight hours a night. This finding impresses how important it is to prioritize sleep in midlife—which is unfortunately the time when family and professional circumstances encourage us to do the exact opposite.
P172: At fault were the two characters, leptin and ghrelin. Inadequate sleep decreased concentrations of the satiety- signaling hormone leptin and increased levels of the hunger-instigating hormone ghrelin. It was a classic case of physiological double jeopardy: participants were being punished twice for the same offense of short sleeping: once by having the “I’m full” signal removed from their system, and once by gaining the “I’m still hungry” feeling being amplified. As a result, participants just didn’t feel satisfied by food when they were short sleeping
P177 : The upshot of all this work can be summarized as follows: short sleep (of the type that many adults in first-world countries commonly and routinely report) will increase hunger and appetite, compromise impulse control within the brain, increase food consumption (especially of high-calorie foods), decrease feelings of food satisfaction after eating, and prevent effective weight loss when dieting.
P213 : In this different and additional role, we can think of REM sleep like a master piano tuner, one that readjusts the brain’s emotional instrumentation at night to pitch-perfect precision, so that when you wake up the next morning, you
can discern overt and subtly covert micro-expressions with exactitude. Deprive an individual of their REM-sleep dreaming state, and the emotional tuning curve of the brain loses its razor-sharp precision. Like viewing an image
through frosted glass, or looking at an out-of-focus picture, a dream-starved brain cannot accurately decode facial expressions, which become distorted. You begin to mistake friends for foes.
P226 : Computers can store thousands of individual files with precision. But standard computers do not intelligently interlink those files in numerous and creative combinations. Instead, computer files sit like isolated islands. Our human memories are, on the other hand, richly interconnected in webs of associations that lead to flexible, predictive powers. We have REM sleep, and the act of dreaming, to thank for much of that inventive hard work
P229 : Like an insightful interviewer, dreaming takes the approach of interrogating our recent autobiographical experience and skillfully positioning it within the context of past experiences and accomplishments, building a rich tapestry of meaning. “How can I understand and connect that which I have recently learned with that I already know, and in doing so, discover insightful new links and revelations?” Moreover, “What have I done in the past that might be useful in potentially solving this newly experienced problem in the future?” Different from solidifying memories, which we now realize to be the job of NREM sleep, REM sleep, and the act of dreaming, takes that which we have learned in one experience setting and seeks to apply it to others stored in memory.
P263: Beyond longer commute times and “sleep procrastination” caused by lateevening television and digital entertainment—both of which are not unimportant in their top-and-tail snipping of our sleep time and that of our
children—five key factors have powerfully changed how much and how well we sleep: (1) constant electric light as well as LED light, (2) regularized temperature, (3) caffeine (discussed in chapter 2), (4) alcohol, and (5) a legacy of punching time cards. It is this set of societally engineered forces that are responsible for many an individual’s mistaken belief that they are suffering from medical insomnia.
P270 : First, alcohol fragments sleep, littering the night with brief awakenings. Alcohol-infused sleep is therefore not continuous and, as a result, not restorative. Unfortunately, most of these nighttime awakenings go unnoticed by the sleeper since they don’t remember them. Individuals therefore fail to link alcohol consumption the night before with feelings of next-day exhaustion caused by the undetected sleep disruption sandwiched in between. Keep an
eye out for that coincidental relationship in yourself and/or others. Second, alcohol is one of the most powerful suppressors of REM sleep that we know of. When the body metabolizes alcohol it produces by-product chemicals called aldehydes and ketones. The aldehydes in particular will block the brain’s ability to generate REM sleep. It’s rather like the cerebral version of cardiac arrest, preventing the pulsating beat of brainwaves that otherwise power dream sleep. People consuming even moderate amounts of alcohol in the afternoon and/or evening are thus depriving themselves of dream sleep.
P279 : Waking up at the same time of day, every day, no matter if it is the week or weekend is a good recommendation or maintaining a stable sleep schedule if you are having difficulty with sleep. Indeed, it is one of the most consistent and effective ways of helping people with insomnia get better sleep. This unavoidably means the use of an alarm clock for many individuals. If you do use an alarm clock, do away with the snooze function, and get in the habit of waking up only once to spare your heart the repeated shock.
P289 : Currently, the most effective of these is called cognitive behavioral therapy for insomnia […] The obvious methods involve reducing caffeine and alcohol intake, removing screen technology from the bedroom, and having a cool bedroom. In addition, patients must (1) establish a regular bedtime and wake-up time, even on weekends, (2) go to bed only when sleepy and avoid sleeping on the couch early/mid-evenings, (3) never lie awake in bed for a significant time period; rather, get out of bed and do something quiet and relaxing until the urge to sleep returns, (4) avoid daytime napping if you are having difficulty sleeping at night, (5) reduce anxiety-provoking thoughts and worries by learning to mentally decelerate before bed, and (6) remove visible clockfaces from view in the bedroom, preventing clock-watching anxiety at night.
P291 : if you can only adhere to one of these each and every day, make it: going to bed and waking up at the same time of day no matter what. It is perhaps the single most effective way of helping improve your sleep, even though it involves the use of an alarm clock.
P298 : Interestingly, participants in the above studies do not perceive themselves as applying less effort to the work challenge, or being less effective, when they were sleep-deprived, despite both being true. They seemed unaware of their poorer work effort and performance—a theme of subjective misperception of ability when sleep-deprived that we have touched upon previously in this book. Even the simplest daily routines that require slight effort, such as time
spent dressing neatly or fashionably for the workplace, have been found to decrease following a night of sleep loss.V Individuals also like their jobs less when sleep-deprived—perhaps unsurprising considering the mood-depressing
influence of sleep deficiency. Under-slept employees are not only less productive, less motivated, less creative, less happy, and lazier, but they are also more unethical.
Conclusion : Within the space of a mere hundred years, human beings have abandoned their biologically mandated need for adequate sleep—one that evolution spent 3,400,000 years perfecting in service of life-support functions. As a result, the decimation of sleep throughout industrialized nations is having a catastrophic impact on our health, our life expectancy, our safety, our productivity, and the education of our children. This silent sleep loss epidemic is the greatest public health challenge we face in the twenty-first century in developed nations. If we wish to avoid the
suffocating noose of sleep neglect, the premature death it inflicts, and the sickening health it invites, a radical shift in our personal, cultural, professional, and societal appreciation of sleep must occur. I believe it is time for us to reclaim our right to a full night of sleep, without embarrassment or the damaging stigma of laziness. In doing so, we can be
reunited with that most powerful elixir of wellness and vitality, dispensed through every conceivable biological pathway. Then we may remember what it feels like to be truly awake during the day, infused with the very deepest
plenitude of being.